NFL Week 2 odds and betting lines: Bengals underdogs vs. Chiefs after shocking loss to Pats

NFL Week 2 odds

We’re only a week into the NFL season, and yet plenty of exciting, disappointing and unpredictable things have already happened.

The latest: Jordan Love suffered a knee injury late in Green Bay’s loss to the Philadelphia Eagles, which will certainly alter the expectations for the Packers over the next few weeks. And the Cincinnati Bengals should feel desperate to bounce back after a stunning home loss to the New England Patriots.

Check out the latest NFL Week 2 odds below.

NFL Week 2 odds

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New Orleans Saints vs. Dallas Cowboys

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Las Vegas Raiders vs. Baltimore Ravens

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New York Giants vs. Washington Commanders

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Los Angeles Chargers vs. Carolina Panthers

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Indianapolis Colts vs. Green Bay Packers

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San Francisco 49ers vs. Minnesota Vikings

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Cleveland Browns vs. Jacksonville Jaguars

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Seattle Seahawks vs. New England Patriots

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New York Jets vs. Tennessee Titans

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Tampa Bay Buccaneers vs. Detroit Lions

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Los Angeles Rams vs. Arizona Cardinals

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Cincinnati Bengals vs. Kansas City Chiefs

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Pittsburgh Steelers vs. Denver Broncos

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Chicago Bears vs. Houston Texans

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Atlanta Falcons vs. Philadelphia Eagles

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Betting insights

  • Well, it’s Malik Willis’ time until further notice in Titletown. Green Bay will be without the injured Jordan Love for at least a few weeks, starting with a home date against Anthony Richardson and the Colts. The Packers went 3-1 ATS as home underdogs last year, but it could be a different story with a castoff QB under centre.
  • The Cowboys and Saints earned comfortable victories in their respective season openers, but the Cowboys did it on the road. Now Dallas is one of the biggest favourites of the week at home, where it averaged a league-best 36.8 points per game last season.
  • Cincinnati posted the dud of the week, losing outright at home (vs. New England) as the heaviest Week 1 favourite. And there’s no time to breathe, with a rested Kansas City squad due up on the schedule. The Chiefs won and covered at home against the Bengals in 2022 and ’23.
  • Unsurprisingly, the lowest over/under on the slate belongs to the Steelers vs. Broncos game. With Justin Fields and Bo Nix under centre, we could see the defences really take over. Fields and Nix combined for 294 pass yards, zero TDs and two INTs in Week 1.
  • Caleb Williams had an atrocious NFL debut (14-for-29, 93 yards, 0 TDs) but his Bears found a way to win. Now he’ll hit the road to face C.J. Stroud and the Texans on Sunday Night Football. Houston is just 3-6 ATS as a favourite since the start of last year.
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Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.