Christian McCaffrey is back.
The pregame narrative: The reigning Offensive Player of the Year missed nine weeks with calf injuries and should provide an immediate boost to the San Francisco 49ers against the Tampa Bay Buccaneers.
Check out our Christian McCaffrey props, odds and best bet for Week 10 vs. Tampa Bay.
Christian McCaffrey props
Click linked odds to add selection to your betslip. Note: Lines have changed/market no longer available if grey.
| McCaffrey prop markets | Betting odds |
| Over 65.5 rushing yards | -115 |
| Under 65.5 rushing yards | -113 |
| Over 14.5 rushing attempts | -117 |
| Under 14.5 rushing attempts | -112 |
| Over 24.5 receiving yards | -114 |
| Under 24.5 receiving yards | -114 |
| Over 93.5 rushing and receiving yards | -115 |
| Under 93.5 rushing and receiving yards | -113 |
| Anytime TD scorer | -250 |
| To score 2+ TDs | +295 |
| To score 3+ TDs | +1,300 |
NFL odds as of 2:02 p.m. ET on 11/09/2024.
McCaffrey literally and figuratively ran away with the OPOY trophy last season, leading the NFL in:
- Touchdowns (21)
- Rushing yards (1,459)
- Scrimmage yards (2,023)
- Touches (339)
He also toted the ball at an impressive 4.5 YPC, was second in RB receiving yards (564), and had a 17-game touchdown streak dating back to the 2022 season.
CMC’s role as a modern-day bell-cow is impressive but it might have also contributed to his long layoff.
He had 24-plus touches (rushes/receptions) in all three of San Francisco’s playoff games and experienced bilateral Achilles tendinitis in training camp.
The Niners are 22-5 all-time with McCaffrey in the lineup and are 4-5 this year without him. That says just about all you need to know.
Best McCaffrey prop bet
Best Bet: McCaffrey under 14.5 rushing attempts (-112)
Maybe I’ll look stupid for taking this postgame but I can’t imagine McCaffrey immediately returning to his old workload.
The Niners’ goal this season is simple: Win the Super Bowl.
We’ve seen that won’t be possible with McCaffrey out of the lineup, so Kyle Shanahan would be wise to treat his superstar with kid gloves.
San Francisco is a 6.5-point favourite over a Tampa Bay team ravaged by injuries. Mike Evans and Chris Godwin are out and I can see a blowout brewing in Florida.
Even if this game is close, rookie RB Isaac Guerendo has been flashing for the Niners. He has gone for 85-plus yards both times he’s received 10-plus carries and is churning out a huge 6.1 YPC on the season.
Finally, this line hasn’t been quite “automatic” for McCaffrey in regular-season games.
He is 17-10 against it in 27 games with SF and had either 15 or 16 carries in four of those contests.
Pick made at 2:02 p.m. ET on 10/07/2024.
Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.