Another four-pack of CFL matchups is due up from Thursday through Saturday, concluding with the Saskatchewan Roughriders visiting the Hamilton Tiger-Cats.
The latest: Saskatchewan went 2-0 ATS against Hamilton last year in a pair of high-scoring games. Both matchups totalled 56-plus points. Earlier on, Nathan Rourke looks to stay sharp against the Winnipeg Blue Bombers, who’ve had his number in the past.
Check out the latest CFL Week 2 predictions for the games beginning Thursday, June 12.
CFL Week 2 predictions
Roughriders over 26.5 points (-137): Saskatchewan kept its pocket clean last week, allowing zero sacks in a 31-point display against the Ottawa Redblacks.
Now the Riders will face 2024’s worst scoring defence, the Tiger-Cats (30.9 PPG).
Hamilton coughed up 38 points and 428 yards in its season opener against the Calgary Stampeders.
In a pair of head-to-head matchups last June, Saskatchewan scored 69 total points against Hamilton and cashed this bet both times.
The Riders lost starting running back A.J. Ouellette during last week’s game, but he practiced in full on Wednesday and should be able to go.
CFL Week 2 best bets
Alouettes -4 (-110): The Montreal Alouettes kicked off their season with a commanding win over the defending champion Toronto Argonauts. Not a bad place to start.
The Als were 5.5-point home favourites against Toronto and covered that line easily in a 28-10 win. They rushed for 6.3 yards per carry and forced three turnovers while keeping the Argos out of the end zone until the fourth quarter.
Up next is a road date with the Redblacks, who’ll play without starting quarterback Dru Brown.
Ottawa lost its Week 1 matchup in Saskatchewan by five points, but Brown’s exploits are the only reason it was even close. He completed 34 of 41 passes for 413 yards and two touchdowns.
Matt Shiltz, a career backup who broke in with Montreal back in 2017, will get the start for Ottawa.
Montreal went 3-0 ATS vs. Ottawa last season, posting a +45 point differential in those matchups. In their past eight meetings (since Oct. 14, 2022), the Alouettes are 7-1 ATS against the Redblacks.
Lions over 25.5 points (-117): BC Lions fans remember the magic Rourke brought to Vancouver in 2022, and he seems capable of capturing that a few seasons later.
The Ohio University grad had a cup of coffee on some NFL rosters in 2023-24 before returning to the Lions in the middle of last season. Without much ramp-up time, he struggled more than expected.
Still, BC cleared this point total in five of his eight starts last year. And thanks to his 324 yards on 27-of-36 passing in Week 1, the Lions earned a 31-14 win in their ’25 season opener.
If you believe that Rourke’s resurgence is for real, this is an attainable number for his Lions to clear.
CFL Week 2 predictions as of 3:57 p.m. on 06/12/2025.
Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.