Week 6 begins with an NFC West clash between the San Francisco 49ers and Seattle Seahawks.
The pregame narrative: Seattle is on a two-game losing streak but is worth backing on an alternate spread at home. I’m also targeting Geno Smith, Zach Charbonnet and Deebo Samuel on the prop market.
Check out my 49ers vs. Seahawks same-game parlay predictions for Week 6 below.
49ers vs. Seahawks same-game parlay predictions
Full Thursday Night Football betting markets: Click here
Parlay: Seahawks +7.5 + Smith over 209.5 passing yards + Charbonnet over 30.5 rushing and receiving yards + Samuel over 59.5 rushing and receiving yards (+360)
Seahawks +7.5 (-210): Neither the Seahawks nor the 49ers are playing their best football right now so I’m happy to bank points with the home team.
Seattle has lost back-to-back games while San Francisco has dropped three of its last four. The 49ers offence doesn’t look quite right without Christian McCaffrey and the defence has folded multiple times down the stretch of close games.
Talanoa Hufanga, Dre Greenlaw and Javon Hargrave are all out and that takes the teeth out of what was an elite unit last season.
Seattle has enough weapons on the offensive side that it should be able to score and keep this close.
Other parlay picks
Smith over 209.5 passing yards (-425): Smith started his season with a 171-yard effort against the Denver Broncos but has blown by this mark in every game since.
He’s thrown for at least 284 yards in each of his last four starts while completing passes above a 70% clip. Smith is also throwing the ball close to 40 times per game, which gives us a lot of room to work with.
The 49ers have a better passing defence than a rushing defence but this should still be well within Smith’s range, hence the -425 odds.
Charbonnet over 30.5 rushing and receiving yards (-112): Kenneth Walker III is Seattle’s definitive RB1 but Charbonnet certainly makes an impact.
The second-year back is averaging 60.2 scrimmage yards per game and has particularly excelled out of the backfield. He’s caught 18 passes for a total of 134 yards (26.8 per game) while rushing for 4.3 yards per carry.
San Francisco is a pedestrian 20th in defensive EPA per rush, per RBSDM.com, and has allowed the seventh-most receiving yards per game to running backs.
On a short week, Mike Macdonald should lean on a rotation with Charbonnet and Walker.
Samuel over 59.5 rushing and receiving yards (-210): Samuel owns the Seahawks.
The dynamic receiver has blown by this line in four straight games against Seattle, averaging 126.3 scrimmage yards in those contests.
He’s coming off his worst game in recent memory, where he logged just 20 scrimmage yards on one catch and three rushing attempts in a loss.
But Samuel still played in 81% of snaps and if he remains at that level — and there’s no reason why he shouldn’t — this is within reach.
Picks made at 10:45 a.m. on 10/10/24.
Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.