{"id":387628,"date":"2025-12-21T10:32:59","date_gmt":"2025-12-21T15:32:59","guid":{"rendered":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/?p=387628"},"modified":"2025-12-21T10:34:54","modified_gmt":"2025-12-21T15:34:54","slug":"49ers-vs-colts-week-16-mnf-sgp-predictions-2025","status":"publish","type":"post","link":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/49ers-vs-colts-week-16-mnf-sgp-predictions-2025\/","title":{"rendered":"49ers vs. Colts MNF Week 16 SGP predictions: Back Taylor and McCaffrey at +295"},"content":{"rendered":"\n<p>Two of the game&#8217;s best running backs clash on Monday Night Football when Jonathan Taylor&#8217;s Indianapolis Colts host Christian McCaffrey&#8217;s San Francisco 49ers.<\/p>\n\n\n\n<p><strong>The pregame narrative:<\/strong> Indianapolis&#8217; playoff hopes would be virtually non-existent with a loss, and hinge on 44-year-old Philip Rivers, who is making his second start since coming out of retirement. San Francisco is on a four-game winning streak and is a sizeable road favourite. <\/p>\n\n\n\n<p>Check out my 49ers vs. Colts predictions, featuring a prop on both RBs in this +295 SGP.<\/p>\n\n\n\n<p class=\"acq_only\"><strong>-&gt; <a href=\"https:\/\/online.northstarbets.ca\/page?key=ej0xMzUyNDU3MiZsPTEzNjY1NzMyJnA9MzExMjU%3D\">Join NorthStar Bets to start betting on the NFL<\/a><\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">49ers vs. Colts predictions<\/h2>\n\n\n\n<p><strong>SGP: 49ers -6.5 | McCaffrey anytime TD | Taylor over 2.5 receptions (+290)<\/strong><\/p>\n\n\n\n<p><strong><strong><strong><strong>49ers -6.5 <\/strong><\/strong><\/strong>(+102):<\/strong> Rivers and the Colts nearly toppled the NFC-best Seattle Seahawks on the road last week, so you would think they have a puncher&#8217;s chance of beating the Niners at home.<\/p>\n\n\n\n<p>But I don&#8217;t. Rivers was extremely immobile and struggled to put any power or speed behind his throws. It&#8217;s sort of what you would expect from a man who was out of the league for five years.<\/p>\n\n\n\n<p class=\"acq_only\"><strong>-&gt; <a href=\"https:\/\/online.northstarbets.ca\/page?key=ej0xMzUyNDU3MiZsPTEzNjY1NzMyJnA9MzExMjU%3D\">Bet on Monday Night Football<\/a><\/strong><\/p>\n\n\n\n<p>The Niners have averaged 31.0 PPG during their four-game winning streak and should be able to put up a boatload of points against the Colts&#8217; defence.<\/p>\n\n\n\n<p>Indianapolis is missing several big names on that side of the ball, especially in the secondary, with Sauce Gardner headlining the inactives.<\/p>\n\n\n\n<p>I just can&#8217;t picture Rivers keeping pace with San Francisco.  <\/p>\n\n\n\n<p class=\"product_only\"><a href=\"cacheembed:122305\">Embed: #122305<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Monday Night Football SGP picks<\/h3>\n\n\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>McCaffrey anytime TD<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong> <strong>(-210):<\/strong> McCaffrey is still as reliable as they come for finding the end zone.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>He&#8217;s scored 14 times this year<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>That includes five of his last six games, where he has eight total TDs. <\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Since joining the 49ers, CMC has 53 touchdowns in 51 regular-season and playoff games.<\/li>\n<\/ul>\n\n\n\n<p>Kyle Shanahan isn&#8217;t shy to give his bell cow looks, as McCaffrey touches the ball 24.6 times per game.<\/p>\n\n\n\n<p>With that type of volume, and Purdy&#8217;s ability to move the ball down the field, he&#8217;s always in a good spot to find pay dirt.<\/p>\n\n\n\n<p><strong>-&gt;<\/strong><a href=\"https:\/\/online.northstarbets.ca\/page?key=ej0xMzUyNDU3MiZsPTEzNjY1NzMyJnA9MzExMjU%3D\"><strong>Back McCaffrey at NorthStar Bets<\/strong><\/a><\/p>\n\n\n\n<p><strong><strong><strong><strong><strong>Taylor over 2.5 receptions<\/strong><\/strong><\/strong><\/strong><\/strong> <strong>(-175):<\/strong> Shane Steichen, much like Shanahan, will want to feed his star RB however possible.<\/p>\n\n\n\n<p>Taylor will obviously get a ton of touches as a rusher, but should be active as a pass-catching back on Monday.<\/p>\n\n\n\n<p>Rivers didn&#8217;t have much time to throw last week, and he isn&#8217;t going to scramble. That means check-downs will become available, and many should be directed to JT.<\/p>\n\n\n\n<p><strong>-&gt; <a href=\"https:\/\/online.northstarbets.ca\/page?key=ej0xMzUyNDU3MiZsPTEzNjY1NzMyJnA9MzExMjU%3D\">Visit NorthStar Bets to see all MNF player props<\/a>!<\/strong><\/p>\n\n\n\n<p>Taylor caught three of his four targets last week and has generally been reliable against this number.<\/p>\n\n\n\n<p>He has two-plus catches in 13 of 14 games, going over this mark nine times. <\/p>\n\n\n\n<p><em>49ers vs. Colts <span style=\"box-sizing: border-box; margin: 0px; padding: 0px;\">predictions&nbsp;made<\/span> at 2:36 p.m. ET on Dec. 21, 2025.<\/em><\/p>\n\n\n\n<p><strong>-&gt; <\/strong><a href=\"https:\/\/online.northstarbets.ca\/page?key=ej0xMzUyNDU3MiZsPTEzNjY1NzMyJnA9MzExMjU%3D\"><strong>Sign up to NorthStar Bets today<\/strong><\/a><strong>!<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Two of the game&#8217;s best running backs clash on Monday Night Football when Jonathan Taylor&#8217;s Indianapolis Colts host Christian McCaffrey&#8217;s San Francisco 49ers. The pregame narrative: Indianapolis&#8217; playoff hopes would be virtually non-existent with a loss, and hinge on 44-year-old Philip Rivers, who is making his second start since coming out of retirement. San Francisco [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":387633,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"sidebar_plugin_meta_block_field":"","footnotes":""},"categories":[61],"tags":[181],"class_list":["post-387628","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nfl","tag-nfl"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>49ers vs. Colts predictions: 2025 MNF SGP | The Boost<\/title>\n<meta name=\"description\" content=\"Check out our 2025 Week 16 49ers vs. Colts SGP predictions. 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