{"id":379261,"date":"2025-11-04T10:41:33","date_gmt":"2025-11-04T15:41:33","guid":{"rendered":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/?p=379261"},"modified":"2025-11-04T10:41:33","modified_gmt":"2025-11-04T15:41:33","slug":"nfl-week-10-upset-picks-and-predictions-2025-season","status":"publish","type":"post","link":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/","title":{"rendered":"NFL Week 10 upset picks: Back the Eagles to win on Monday Night Football"},"content":{"rendered":"\n<p>Coming off a hideous loss at home, the Green Bay Packers are somehow favoured against the defending champion Philadelphia Eagles.<\/p>\n\n\n\n<p><strong>The pregame narrative<\/strong>: On Monday Night Football, Philly faces a Green Bay squad that&#8217;s missing one of its best offensive weapons. In Sunday&#8217;s action, look for the San Francisco 49ers to contend against a Los Angeles Rams squad they&#8217;ve already beaten this year.<\/p>\n\n\n\n<p>Check out my top NFL Week 10 upset picks for games on Nov. 9-10.<\/p>\n\n\n\n<p class=\"acq_only\"><strong>-> <a href=\"https:\/\/online.northstarbets.com\/promoRedirect?key=ej0xMzUyNTA0MiZsPTEzNTI1MDAwJnA9ODMzNw%3D%3D\">Join NorthStar Bets and start wagering on the NFL<\/a><\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"block-0a4ee124-09d4-4260-81c9-fd6fe232dbb3\">NFL Week 10 upset picks<\/h2>\n\n\n\n<p id=\"block-479767b6-5872-497b-ac44-239c07c7e3d5\"><strong>Best bet: Eagles moneyline (+112)<\/strong><\/p>\n\n\n\n<p>This is the first time the Eagles have been underdogs all season. But why now?<\/p>\n\n\n\n<p>Sure, Green Bay (5-2-1) is at home, but Philly (6-2) has the better record and is coming off a bye. The Eagles are also 3-0 vs. the Packers since 2022, with a pair of wins last season.<\/p>\n\n\n\n<p class=\"acq_only\"><strong>-> <a href=\"https:\/\/online.northstarbets.com\/promoRedirect?key=ej0xMzUyNTA0MiZsPTEzNTI1MDAwJnA9ODMzNw%3D%3D\">Wager on NFL Week 10 at NorthStar Bets<\/a><\/strong><\/p>\n\n\n\n<p>Oh, and let&#8217;s not forget the abomination of a performance from Green Bay&#8217;s offence in Week 9. With the Carolina Panthers in town, the Packers scored just 13 points in a losing effort.<\/p>\n\n\n\n<p>Green Bay was <em>favoured<\/em> by 13.5 points, mind you. It was by far the NFL&#8217;s biggest upset of the season.<\/p>\n\n\n\n<p>The Packers just lost tight end Tucker Kraft (knee) for the year. It&#8217;d be difficult to overstate the value of Kraft, who&#8217;s third in the NFL in yards after catch (344 YAC).<\/p>\n\n\n\n<p>None of Green Bay&#8217;s wide receivers has even 100 YAC this season.<\/p>\n\n\n\n<p>Philadelphia hasn&#8217;t looked as dominant as people might expect from a defending champion, but the team has stacked wins over some impressive teams: Chiefs, Rams and Buccaneers.<\/p>\n\n\n\n<p>It&#8217;s tough to expect a proper bounce back from the Packers&#8217; offence in their first game without Kraft. The rested Eagles should take advantage.<\/p>\n\n\n\n<p><strong>Key stat<\/strong>: The Eagles rushed for 140+ yards in both games vs. Green Bay last year and won those matchups by a combined 17 points.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"block-fa134a48-a478-432b-95e0-66881f0d337b\">NFL underdog predictions<\/h3>\n\n\n\n<p><strong>49ers moneyline (+150):<\/strong> San Francisco routinely has a laundry list of injuries to contend with, but a couple of key names could be back in the fold for Week 10.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>QB Brock Purdy, who has only played in two games this year, practiced all of last week and seems likely to return Sunday.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>WR Ricky Pearsall, who&#8217;s averaging 80+ yards per game but hasn&#8217;t played since September, &#8220;has a chance to play,&#8221; according to head coach Kyle Shanahan.<\/li>\n<\/ul>\n\n\n\n<p class=\"acq_only\"><strong>-> <a href=\"https:\/\/online.northstarbets.com\/promoRedirect?key=ej0xMzUyNTA0MiZsPTEzNTI1MDAwJnA9ODMzNw%3D%3D\">Don&#8217;t miss out \u2014 Bet on the NFL now at NorthStar Bets<\/a>!<\/strong><\/p>\n\n\n\n<p>The Rams are a tough team to stop, but the Niners already have a win over them this season (26-23 in L.A. in Week 5). And that was with Mac Jones at quarterback.<\/p>\n\n\n\n<p>With a top-10 scoring defence, the Niners won&#8217;t be doormats for the Rams&#8217; loaded offence. And if Purdy\/Pearsall return, expect San Francisco&#8217;s offence to make some noise, too.<\/p>\n\n\n\n<p><em>NFL upset picks made at 10:40 a.m. ET on 11\/04\/2025.<\/em><\/p>\n\n\n\n<p class=\"acq_only\"><strong>-> <a href=\"https:\/\/online.northstarbets.com\/promoRedirect?key=ej0xMzUyNTA0MiZsPTEzNTI1MDAwJnA9ODMzNw%3D%3D\">Sign up to NorthStar Bets today<\/a>!<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Coming off a hideous loss at home, the Green Bay Packers are somehow favoured against the defending champion Philadelphia Eagles. The pregame narrative: On Monday Night Football, Philly faces a Green Bay squad that&#8217;s missing one of its best offensive weapons. In Sunday&#8217;s action, look for the San Francisco 49ers to contend against a Los [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":379257,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"sidebar_plugin_meta_block_field":"","footnotes":""},"categories":[452,61],"tags":[],"class_list":["post-379261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-com","category-nfl"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NFL Week 10 upset picks: 2025 underdog predictions | The Boost<\/title>\n<meta name=\"description\" content=\"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NFL Week 10 upset picks: 2025 underdog predictions | The Boost\" \/>\n<meta property=\"og:description\" content=\"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/\" \/>\n<meta property=\"og:site_name\" content=\"The Boost\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-04T15:41:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2025\/11\/CP173824776.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"2092\" \/>\n\t<meta property=\"og:image:height\" content=\"1395\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Jordan Horrobin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@JordanHorrobin\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jordan Horrobin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/\",\"url\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/\",\"name\":\"NFL Week 10 upset picks: 2025 underdog predictions | The Boost\",\"isPartOf\":{\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#website\"},\"datePublished\":\"2025-11-04T15:41:33+00:00\",\"dateModified\":\"2025-11-04T15:41:33+00:00\",\"author\":{\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/8e0d7302b14f65be7f61f221a134fc9f\"},\"description\":\"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.\",\"inLanguage\":\"en-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#website\",\"url\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/\",\"name\":\"The Boost\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-CA\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/8e0d7302b14f65be7f61f221a134fc9f\",\"name\":\"Jordan Horrobin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-CA\",\"@id\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2024\/11\/IMG_7764.jpg\",\"contentUrl\":\"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2024\/11\/IMG_7764.jpg\",\"caption\":\"Jordan Horrobin\"},\"description\":\"Jordan enjoys writing data-driven game previews and analysis articles \u2014 especially for MLB markets or NFL\/NBA props. And as a proud Ohio University grad, he\u2019ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.\",\"sameAs\":[\"https:\/\/www.northstarbets.ca\/sportsbook\/news\",\"https:\/\/twitter.com\/JordanHorrobin\"],\"url\":\"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/author\/jordan-horrobinnorthstargaming-ca\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NFL Week 10 upset picks: 2025 underdog predictions | The Boost","description":"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/","og_locale":"en_US","og_type":"article","og_title":"NFL Week 10 upset picks: 2025 underdog predictions | The Boost","og_description":"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.","og_url":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/","og_site_name":"The Boost","article_published_time":"2025-11-04T15:41:33+00:00","og_image":[{"width":2092,"height":1395,"url":"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2025\/11\/CP173824776.webp","type":"image\/webp"}],"author":"Jordan Horrobin","twitter_card":"summary_large_image","twitter_creator":"@JordanHorrobin","twitter_misc":{"Written by":"Jordan Horrobin","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/","url":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/","name":"NFL Week 10 upset picks: 2025 underdog predictions | The Boost","isPartOf":{"@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#website"},"datePublished":"2025-11-04T15:41:33+00:00","dateModified":"2025-11-04T15:41:33+00:00","author":{"@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/8e0d7302b14f65be7f61f221a134fc9f"},"description":"Check out our 2025 NFL Week 10 upset picks. Football betting odds and underdog predictions on the Eagles and 49ers.","inLanguage":"en-CA","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-10-upset-picks-and-predictions-2025-season\/"]}]},{"@type":"WebSite","@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#website","url":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/","name":"The Boost","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-CA"},{"@type":"Person","@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/8e0d7302b14f65be7f61f221a134fc9f","name":"Jordan Horrobin","image":{"@type":"ImageObject","inLanguage":"en-CA","@id":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/#\/schema\/person\/image\/","url":"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2024\/11\/IMG_7764.jpg","contentUrl":"https:\/\/nsb-news.s3.ca-central-1.amazonaws.com\/imgs\/2024\/11\/IMG_7764.jpg","caption":"Jordan Horrobin"},"description":"Jordan enjoys writing data-driven game previews and analysis articles \u2014 especially for MLB markets or NFL\/NBA props. And as a proud Ohio University grad, he\u2019ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.","sameAs":["https:\/\/www.northstarbets.ca\/sportsbook\/news","https:\/\/twitter.com\/JordanHorrobin"],"url":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/author\/jordan-horrobinnorthstargaming-ca\/"}]}},"_links":{"self":[{"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/posts\/379261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/comments?post=379261"}],"version-history":[{"count":2,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/posts\/379261\/revisions"}],"predecessor-version":[{"id":379265,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/posts\/379261\/revisions\/379265"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/media\/379257"}],"wp:attachment":[{"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/media?parent=379261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/categories?post=379261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/wp-json\/wp\/v2\/tags?post=379261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}