{"id":368152,"date":"2025-09-09T14:09:58","date_gmt":"2025-09-09T18:09:58","guid":{"rendered":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/?p=368152"},"modified":"2025-09-09T14:10:10","modified_gmt":"2025-09-09T18:10:10","slug":"nfl-week-2-upset-picks-and-predictions-2025-season","status":"publish","type":"post","link":"https:\/\/cms.northstargaming.ca\/admin\/nsgcms\/nfl-week-2-upset-picks-and-predictions-2025-season\/","title":{"rendered":"NFL Week 2 upset picks: Moneyline underdog predictions on New Orleans Saints, New England Patriots"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Favourites reigned supreme during the first week of NFL action, going 11-4 SU, but I&#8217;ve got my eyes on two upsets for the upcoming slate. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The pregame narrative<\/strong>: The San Francisco 49ers are already dealing with significant injuries, and they now head cross-country to play the Saints in New Orleans. This feels like a spot where Spencer Rattler and Co. can steal a win.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Check out my top Week 2 NFL upset picks, featuring a pick on the New England Patriots vs. Miami Dolphins.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"block-0a4ee124-09d4-4260-81c9-fd6fe232dbb3\">NFL upset picks: Week 2<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.northstarbets.com\/sportsbook\/sports\/american_football\/competitions\/12295\/matches\"><strong>Full NFL markets<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.northstarbets.com\/sportsbook\/news\/stats\/nfl\/top-players\/passing-yards\"><strong>NFL player &amp; team stats<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.northstarbets.com\/sportsbook\/news\/article\/nfl-injury-report-news\"><strong>NFL injury report<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.northstarbets.com\/sportsbook\/news\/stats\/nfl\/standings\"><strong>NFL standings<\/strong><\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"block-479767b6-5872-497b-ac44-239c07c7e3d5\"><strong>Best bet: Saints moneyline (+180)<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">New Orleans isn&#8217;t projected to win many games this season, but I was impressed with the fight its defence put up against the Arizona Cardinals in Week 1.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The Saints&#8217; defence held Arizona to 276 yards in the game and just three points in the second half. <\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Outside of a 52-yard run by Trey Benson, the Cardinals put up just 94 rushing yards on 3.48 yards\/carry.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>New Orleans&#8217; 28.0% defensive rush success rate was the fifth-best among all teams, per RBSDM.com.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">It&#8217;s no secret San Francisco is going to want to run the ball on Sunday, but I&#8217;m skeptical it&#8217;ll be able to do that effectively.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Christian McCaffrey toted the ball 22 times for an inefficient 69 yards in Week 1 against the Seattle Seahawks. He&#8217;ll be asked to do more with George Kittle out and Brock Purdy (toe\/shoulder) questionable.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If Purdy can&#8217;t go, backup Mac Jones will be under centre, and this line will surely move a few points in New Orleans&#8217; direction.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Key stat<\/strong>: San Francisco ranked 27th in offensive EPA per rush in Week 1. <\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"block-fa134a48-a478-432b-95e0-66881f0d337b\">NFL underdog predictions<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>New England moneyline (+105):<\/strong> New England is barely an underdog against Miami, but it&#8217;s an underdog nonetheless. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Dolphins will be back home in Week 2, but I can&#8217;t put any faith in a team that was just dismantled by the Daniel Jones-led Indianapolis Colts.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Miami was down 30-0 into the dying minutes of the fourth quarter before scoring a garbage-time touchdown to avoid a shutout.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It looks like the team has already quit on fourth-year head coach Mike McDaniel and quarterback Tua Tagovailoa.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Patriots are far from a good team, mind you. But I trust Mike Vrabel to get his group going against a divisional rival.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>NFL upset picks made at 11:57 a.m. ET on 09\/09\/2025<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Favourites reigned supreme during the first week of NFL action, going 11-4 SU, but I&#8217;ve got my eyes on two upsets for the upcoming slate. The pregame narrative: The San Francisco 49ers are already dealing with significant injuries, and they now head cross-country to play the Saints in New Orleans. This feels like a spot [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":368092,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"sidebar_plugin_meta_block_field":"","footnotes":""},"categories":[452,61],"tags":[181],"class_list":["post-368152","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-com","category-nfl","tag-nfl"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NFL upset picks: 2025 Week 2 underdog predictions | NSB<\/title>\n<meta name=\"description\" content=\"Check out our 2025 Week 2 NFL upset picks. 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