Top European soccer picks and predictions: Best bets for Serie A opener, Week 2 of EPL and La Liga

Soccer predictions

The European soccer schedule is in full swing, with matches from the Premier League, Serie A and La Liga making their way into this weekend’s predictions.

The pregame narrative: Bournemouth put up a strong effort against Liverpool in its season opener and should build off that with a home win against Wolverhampton. Elsewhere, I expect two European powerhouses — Barcelona and Inter Milan — to dominate the competition.

Check out this weekend’s best European soccer predictions for games beginning on Saturday, Aug. 23, 2025.

Soccer predictions

Matchup: Bournemouth vs. Wolves (Aug. 23, 10 a.m. ET)

Best bet: Bournemouth to win (-125)

Bournemouth is coming off its best-ever Premier League finish, landing ninth in the 2024-25 table with a 15-11-12 record.

The Cherries sold a trio of promising young defenders over the summer, but also spent north of $100 million on replacements.

They should still be a solid side, and we saw some promise last Friday, when Bournemouth was on the brink of stealing points from the defending champions at Anfield.

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Federico Chiesa eventually broke a 2-2 draw in the 88th minute for Liverpool, but I can’t ignore that effort.

Back at home, I love Bournemouth’s chances of beating an awful Wolverhampton side.

The Wolves finished 16th in the table last year and got shelled, 4-0, by Manchester City at home to open the season.

Vítor Pereira’s side will likely be fighting a relegation battle this year, and I expect it to struggle, again, on the road.

Key stat: Wolverhampton went 6-3-10 on the road last year, losing 4-2 to Bournemouth at home.

La Liga best bet

Matchup: Barcelona vs. Levante (Aug. 23, 3:30 p.m. ET)

Barcelona over 2.5 goals (-130): This is a mismatch of epic proportions, and I expect the score to reflect that.

Barcelona is coming off a renaissance season, winning a domestic Treble (La Liga, Copa del Rey, Supercopa de Espana) and beating its arch-rivals Real Madrid in all four El Clasicos.

Hansi Flick’s side led La Liga in these categories last season, according to FotMob:

  • Goals per game (2.7)
  • Possession (69.1%)
  • xG (92.4)
  • SOT per match (6.6)

The loaded offence — led by Robert Lewandowski, Lamine Yamal and Raphinha — shouldn’t have a problem dissecting the back line of the freshly promoted Levante.

Bet on La Liga soccer

Serie A prediction

Matchup: Inter Milan vs. Torino (Aug. 25, 2:45 p.m. ET)

Torino under 0.5 goals (+105): I’m expecting Inter Milan to shut out Torino in Serie A’s opening weekend.

The Nerazzurri had a heartbreaking 2024-25 season, finishing one point behind Napoli for the Scudetto and losing badly to PSG in the Champions League final.

However, Inter is still a great team, built on a strong defence.

Last season, it had the third-most clean sheets (16) while allowing the second-fewest goals per game (0.9) and holding the highest possession (59.8%).

Inter has five clean sheet victories in its last six matches against Torino.

Bet on the new Serie A season

Soccer predictions made at 4:05 p.m. on 08/22/25.

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Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.