Sabalenka vs. Anisimova US Open women’s final odds and best bet: Back the underdog to be competitve against world No. 1

Sabalenka vs. Anisimova odds

Aryna Sabalenka looks to repeat as U.S. Open champion against No. 9-ranked Amanda Anisimova.

The pre-match narrative: Sabalenka won last season but faces a new foe in her title defence. Anisimova should give her a challenge as the two meet for the 10th time in their careers. Despite being lower-ranked, Anisimova has been successful in this matchup in the past.

Check out our Sabalenka vs. Anisimova odds and my best bet for the Sept. 6 tennis match.

Sabalenka vs. Anisimova odds

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Best Bet: Anisimova over 11.5 games won (-113)

I thought about backing Anisimova to win at +185, but opted to go a little safer and take something that can cash even in a loss.

The head-to-head history falls on the side of the American, who is 6-3 in her career against Sabalenka.

Anisimova most recently beat the world No. 1 at Wimbledon earlier in the summer.

That match was contested on grass, but it’s good to know that she holds the advantage on outdoor hardcourts too, winning two of three matches on the surface.

Anisimova has been rolling at the U.S. Open, beating No. 2-ranked Iga Swiatek in the quarterfinal before knocking off a red-hot Naomi Osaka to reach the final.

Sabalenka is the best in the world for a reason, and she’s only dropped one set at this event.

But it was against her only top-25-ranked opponent at Flushing Meadows, No. 4 Jessica Pegula, in Thursday’s semifinal. Pegula won 13 games in the loss.

So, I’ll back Anisimova to be competitive against an opponent she’s had the upper hand on throughout her career.

Key stat: The American has converted 44.1% of her breakpoint opportunities in 2025, which should help her steal games from Sabalenka.

Sabalenka vs. Anisimova best bet made at 2:30 p.m. on 09/05/2025.

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Spencer is a true sports junkie. A graduate of the Sports Journalism program at Centennial College, he first joined NorthStar Gaming as an intern in 2023. He is now a contributing writer. He loves finding the edge to bet on in all sports but has a deep passion for the NBA and UFC. Previous stops include Sportsnet.