Week 7 is here, meaning we’re officially more than a third of the way into the NFL season.
Week 7 at a glance: The slate is stacked with tight matchups, with only one game having a spread larger than a touchdown. Headlining the action is a clash between the Tampa Bay Buccaneers (5-1) and Detroit Lions (4-2) as part of a Monday Night Football doubleheader.
Check out our Week 7 NFL betting guide for staff picks and predictions on the loaded 15-game slate.
NFL betting guide: Week 7 predictions
ATS picks: Get ATS predictions from five different staff writers on every game of the week.
NFL Week 7 TD picks: What’s better than one TD pick on an NFC East running back? Two. Saquon Barkley’s price to score is in a playable spot after some subpar performances, and Avery Perri is jumping on board.
Upset picks: Baker Mayfield has defied the odds all season, and Jordan Horrobin thinks he can author another upset victory in primetime.
Best bets: Kyren Williams headlines this four-pack of NFL best bets, which includes two ATS picks and an over/under bet.
Prop bets: Quinshon Judkins is a workhorse and gets the league’s worst rushing defence in windy conditions. That seems like a recipe for a huge game.
Colts vs. Chargers SGP: Are the 5-1 Colts for real? That’s up for debate, but Jonathan Taylor certainly is. Horrobin is backing the star RB to score in this +335 wager.
Falcons vs. 49ers SNF picks: The last time the Falcons played on the road, they lost 30-0 to the Carolina Panthers. Woof. Now they’ll face a San Francisco squad that welcomes back George Kittle — while Kendrick Bourne looks to continue a Jerry Rice-like run.
Falcons vs. 49ers SNF SGP: Looking for a plus-money play? Psihogios is banking on an Atlanta win as the backbone of his +575 SGP for Sunday Night Football.
Texans vs. Seahawks MNF picks: Why does Zach Charbonnet keep getting prime opportunities for Seattle? Horrobin is more interested in Charbonnet’s anytime TD price than the answer to that question.
Buccaneers vs. Lions MNF picks: Even with a thin receiving corps, Baker Mayfield has shown he can really sling it. And if Jared Goff joins in on the fun, we could have ourselves quite an air show in Detroit on Monday Night Football.
Falcons vs. 49ers SNF SGP: Fading Christian McCaffrey and backing Kyle Pitts is the backbone of this same-game parlay.
Buccaneers vs. Lions MNF SGP: Amon-Ra St. Brown was force-fed in the last two meetings between these teams, making him a strong target to have a game. Backing Mayfield and Tampa Bay on an alt spread rounds out this +370 wager.
Texans vs. Seahawks MNF SGP: Two elite defences are clashing to close out Week 7, and Psihogios is leaning on that in his parlay.
NFL Week 7 betting notes
- Brian Callahan is out in Tennessee. His 4-19 ATS record was the worst mark for any coach in the Super Bowl era. Teams are 11-11 ATS in the week following a coach firing over the past decade.
- The only team favoured by more than a TD: the Chiefs (-12) at home vs. the Raiders. Patrick Mahomes is 13-24-1 ATS as a favourite of 7.5 points or more.
- Bijan Robinson is on pace for 2,794 scrimmage yards. That would be the greatest single-season mark in NFL history by over 250 yards.
- The Seahawks are 3-9 ATS at home since last season, while the Texans are 6-6-1 ATS on the road. Can Sam Darnold overcome that trend against the league’s best scoring defence?
- There are projected to be 50-60 mph wind gusts in Cleveland on Sunday. The Dolphins vs. Browns game has the lowest over/under on the slate at 37.5 points.
Biggest spreads: Raiders vs. Chiefs (-12); Patriots (-7) vs. Titans; Giants vs. Broncos (-7)
Highest totals: Commanders vs. Cowboys (55); Buccaneers vs. Lions (52.5); Colts vs. Chargers (48)
NFL Week 7 matchups

Thursday Night Football (Oct. 16)
- Steelers vs. Bengals (8:15 p.m. ET)
International Series game in London (Oct. 19)
- Rams vs. Jaguars (9:30 a.m. ET)
Sunday, Oct. 19: 1 p.m. ET slate
- Patriots vs. Titans
- Dolphins vs. Browns
- Panthers vs. Jets
- Eagles vs. Vikings
- Raiders vs. Chiefs
- Saints vs. Bears
Sunday, Oct. 19: 4 p.m. ET slate
- Colts vs. Chargers
- Giants vs. Broncos
- Commanders vs. Cowboys
- Packers vs. Cardinals
Sunday Night Football
- Falcons vs. 49ers (8:20 p.m. ET)
Monday Night Football double header (Oct. 20)
- Buccaneers vs. Lions (7:00 p.m. ET)
- Texans vs. Seahawks (10:00 p.m. ET)
Week 7 byes: Buffalo Bills, Baltimore Ravens
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