It’s the smallest Sunday slate of the NFL season so far but still features a double-digit dose of games.
Four teams are on bye and after consecutive weeks with a Monday Night Football doubleheader, we are back to one primetime game to close the slate.
Check out our Week 5 NFL betting guide, featuring staff picks and predictions to help you make the best wagers.
NFL betting guide: Week 5
We rarely get treated to a great Thursday nighter but the kickoff to Week 5 didn’t disappoint. That’s especially true if you were a Falcons backer.
What looked like a surefire loss with under two minutes remaining quickly turned into a tie game as the fourth quarter expired thanks to magic from Kirk Cousins and a 52-yard kick.
Cousins’ wizardry continued into overtime, helping the Falcons win, cover and move into first place in the NFC South in the highest-scoring TNF game of the season.
Will any game top the 66 points the Falcons and Buccaneers combined for? That’s a big ask but there are several large totals, including a 50 on the board as of Friday afternoon.
Some quick betting notes before we dive into everything you could possibly want to bet on in Week 5:
- Highest total: Cardinals vs. 49ers (50)
- Biggest spread: 49ers (-7); Seahawks (-7) vs. Giants
- Three teams have odds of +200 or longer to win (Cardinals, Giants, Saints)
Lines and odds are listed as of 3:10 p.m. ET on Oct. 4. For the latest, check out our NFL Week 5 markets.
Now, see how our staff is wagering on this slate.
Week 5 betting predictions
If you need a one-stop shop for spread bets, we have you covered.
Our NFL Week 5 ATS picks, via Avery Perri, Jordan Horrobin, Spencer Closs and Chris Toman, provide a recommendation against the spread for every game.
We have plenty of other picks, too.
Week 5 best bets: Sunday kicks off early with the Packers and Vikings getting underway at 9:30 a.m. ET in London. Four of the five games played overseas last season went under 40.5 points — Perri likes that trend to continue.
Underdogs: See why Horrobin likes both the Panthers (at Chicago) and Cowboys (at Pittsburgh on Sunday Night Football) to win on the road this week.
Parlay picks: It’s a big +498 parlay, via Closs, featuring the over on two totals and Packers (-162) on the moneyline.
Prop picks: A running back, quarterback and tight end are all featured in this week’s prop recommendations. The QB is Kyler Murray but it’s a play on his rushing output.
Ravens vs. Bengals same-game parlay picks: If there’s such a thing as a must-win game in Week 5, that’s what the Bengals are staring down with this key divisional clash. See who our Stevie Psihogios picked on the moneyline in this +400 ticket.
Bills vs. Texans same-game parlay picks: Two first-place AFC teams collide this Sunday and Perri is serving up a +425 SGP that includes plays on Josh Allen and Nico Collins.
TD picks: Horrobin is targeting three players and one of the picks is a +275 choice to score.
SNF and MNF predictions
Cowboys vs. Steelers best bets: Expect Justin Fields to go off. Perri likes him to produce through the air and on the ground after two efficient passing weeks. A big game from Fields should also mean plenty of points for the Steelers.
Cowboys vs. Steelers prop picks: Najee Harris has found very little success so far, but Horrobin thinks he can finally break out in a plus matchup on Sunday night. Horrobin also has an anytime TD scorer pick and is fading a player on the Cowboys.
Saints vs. Chiefs best bets: Who will step up for the Chiefs after the Rashee Rice injury? Psihogios is counting on a modest effort from Justin Watson, but he’s also taking the under on the game total.
Visit our football vertical for complete NFL coverage, including the latest Super Bowl odds.
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