NFL Week 4 TD picks and predictions: Bhayshul Tuten has value, A.J. Brown should build off breakout

NFL TD picks

A.J. Brown got back to doing A.J. Brown things last week, and I expect another big game out of the Philadelphia Eagles’ WR1.

The pregame narrative: Brown, who broke out in Week 3 after a pair of disappointing performances, should be at the centre of Philly’s offensive plans this Sunday. Later in the day, Bhayshul Tuten and Rome Odunze both hold value as youngsters on the rise.

Check out my top Week 4 NFL TD picks.

NFL TD picks: Week 4

Best bet: Tuten anytime TD (+250)

I think Tuten is teeming with value to score a touchdown in Week 4.

The fourth-round rookie impressed the Jacksonville Jaguars enough to make Tank Bigsby expendable, and now he’s carving out a steady RB2 role for the team.

Travis Etienne will presumably retain the bulk of the touches for the foreseeable future, but Tuten deserves to be involved.

  • Tuten doesn’t have a negative play yet through three weeks.
  • He has a touch inside the 10-yard line in back-to-back games and scored a TD on both.
  • Over the past two games, Tuten has turned 16 total touches into 95 scrimmage yards.

Jacksonville faces the San Francisco 49ers, who have allowed just 16.3 points per game so far (second-lowest in the NFL). So I wouldn’t call this a smash play based on the matchup.

But Tuten is absolutely holding value right now as an emerging rookie who’s making the most of the opportunities in front of him.

Key stat: Tuten received the Jaguars’ lone carry inside the five-yard line in Week 3, and he scored on it.

Best NFL touchdown bets

Brown anytime TD (+135): Brown looked like himself again in Week 3, snagging six catches for 109 yards and a touchdown.

After seeing only nine targets through Weeks 1 and 2 — with zero red zone looks — Brown had 10 targets in Week 3 (including a trio of red zone targets).

Brown and the Eagles will face a Buccaneers defence that has been superb against the run. Tampa Bay’s defence ranks No. 1 in EPA per rush and No. 2 in rush success rate, per RBSDM.com.

If the Eagles’ rushing attack gets jammed up, Brown should get even more chances as the primary option through the air.

Two years ago, in his last matchup against the Bucs, Brown caught nine of 14 targets for 131 yards.

Odunze anytime TD (+140): I think this week’s Raiders/Bears game has shootout potential, and Odunze should be a beneficiary.

Las Vegas’ defence ranks 27th in EPA per dropback and 21st in dropback success rate. This is a team Caleb Williams should be able to throw against.

Speaking of Williams, he’s coming off his best game as a pro (298 yards, four TDs, 142.6 passer rating). One of his four touchdown passes went to Odunze, who led the Bears with seven targets.

  • Odunze has 4 of 9 red zone targets among Chicago WRs.
  • He has 4 TDs on the season, cashing this bet in all three games.
  • He has four catches of 20+ yards in the past two weeks, so there’s big-play potential here, too.

NFL TD picks made at 12:15 p.m. ET on 09/26/2025.

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Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.