The Champions League returns next week with 16 games scattered across three days.
The pre-matchday narrative: A heavyweight tilt between reigning FIFA Club World Cup champions Chelsea and German powerhouse Bayern Munich headlines the action on Wednesday. After that, Barcelona heads to St James’ Park to take on a struggling Newcastle side.
Check out the latest Champions League odds for Matchday 1 below.
Champions League odds and key fixtures
- Juventus has been great defensively since appointing Igor Tudor last season. The squad is currently on a four-game unbeaten run, picking up a 2-1 win over Dortmund in a club friendly in August.
- Liverpool made some massive splashes in the transfer window, acquiring Alexander Isak, Florian Wirtz, and Hugo Ekitike. The Reds were already stacked to begin with and are deserved favourites at Anfield.
- Bayern Munich averaged the second-most xG in the Champions League last year, despite bowing out in the quarterfinal. The Bavarians are unbeaten in 34 straight home games (32-2-0) in the group/league stage of the UEFA Champions League.
- Barcelona was a powerhouse last season, winning a domestic treble before losing out in a high-scoring Champions League semifinal against Inter Milan. Hansi Flick’s side averaged the most goals per game (3.1) in the UCL last year, and Newcastle is winless in its first three EPL fixtures.
UCL Matchday 1 betting lines
Athletic Bilbao (+275) vs. Arsenal (+107)
Sept. 16 12:45 p.m. ET
PSV Eindhoven (-129) vs. Union Saint-Gilloise (+340)
Sept. 16 12:45 p.m. ET
Benfica (-455) vs. Qarabag (+1,400)
Sept. 16 3:00 p.m. ET
Real Madrid (-286) vs. Marseille (+750)
Sept. 16 3:00 p.m. ET
Tottenham (-110) vs. Villarreal (+300)
Sept. 16 3:00 p.m. ET
Olympiakos (-200) vs. Pafos (+600)
Sept. 17 12:45 p.m. ET
Slavia Praha (-110) vs. Bodo Glimt (+275)
Sept. 17 12:45 p.m. ET
Ajax (+310) vs. Inter Milan (-114)
Sept. 17 3:00 p.m. ET
PSG (-250) vs. Atalanta (+700)
Sept. 17 3:00 p.m. ET
Club Brugge (+165) vs. AS Monaco (+155)
Sept. 18 12:45 p.m. ET
FC Copenhagen (+255) vs. Bayer Leverkusen (+120)
Sept. 18 12:45 p.m. ET
Eintracht Frankfurt (+110) vs. Galatasary (+230)
Sept. 18 3:00 p.m. ET
Manchester City (-141) vs. Napoli (+380)
Sept. 18 3:00 p.m. ET
Sporting Lisbon (-835) vs. Kairat Almaty (+2,500)
Sept. 18 3:00 p.m. ET
Champions League betting market
UCL odds as of 2:20 p.m. ET on 09/11/2025.
Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.