The action at the US Open is heating up as the men’s and women’s draws whittle down.
The pregame narrative: Felix Auger-Aliassime is playing some great tennis, but a difficult matchup against Andrey Rublev awaits. Jannik Sinner is a buzzsaw, but I’m betting on Alexander Bublik to stay competitive.
Check out my top 2025 U.S. Open picks for the round of 16, featuring a pick on Naomi Osaka vs. Coco Gauff.
US Open picks: Round of 16
Best Bet: Rublev -1.5 sets (+137)
On paper, this is a very even matchup.
Auger-Aliassime has been cruising at the US Open. He’s only dropped one set at the tournament and has now won six of his last seven matches.
Rublev has dropped three sets at Flushing Meadows but has also won six of his last seven outings.
So why would I back Rublev to win by this margin?
It’s hard to ignore the head-to-head history between these two.
Rublev has absolutely had his number. He’s beaten the Canadian in seven of their eight duels, including each of their last five showdowns.
Five of their matches have been on the hardcourts, with Rublev taking four of them.
Despite his recent run of success at the US Open, Auger-Aliassime hasn’t been lighting it up on the hardcourts either. He’s 25-18 on the surface since 2024, while Rublev is a much more impressive 42-20.
Bet on Rublev to advance with relative ease against Auger-Aliassime.
Key stat: Rublev’s serve has been excellent, totalling 36 aces across his last two matches.
US Open best bets
Bublik +2.5 sets (+100): Sinner is a massive favourite in this match (-1,430) and rightfully so.
He’s automatic at majors, advancing to the final at each of the last four tournaments.
And while I expect him to win this match, don’t discount how well Bublik is playing.
The Kazakhstani star has won 11 consecutive contests, winning nine of those contests via straight sets. He’s also held his own historically against Sinner, winning two of their last three head-to-head battles.
That includes the most recent meeting between the two, a three-set victory at the Terra Wortmann Open.
Getting Bublik at even money to win a set is a fair price.
Gauff -1.5 sets (+150): Few players have done a better job raising their stock in 2025 than Osaka.
The Japanese star is 30-12 overall and 19-6 on the hardcourts. She’s coming off a finals appearance at the National Bank Open and has won nine of her last 10 matches.
But there’s one thing that’s evaded Osaka. Success at the majors.
Osaka hasn’t done very well at Grand Slam events this year, failing to advance past the third round at each tournament.
She also hasn’t fared well against Gauff.
Osaka has lost three of her last four matches against Gauff in straight sets, with all coming on the hardcourts.
Bet on Gauff, who has only lost one set at Flushing Meadows, to emerge victorious again.
US Open picks made at 4:01 p.m. on 08/31/2025.