The new NFL week begins with an NFC West matchup between the Seattle Seahawks and the Arizona Cardinals.
The pregame narrative: Every team in the division is above .500, so a win here will be crucial for either side. Despite being on the road, I like Seattle’s chances of emerging from Thursday Night Football with a 3-1 record.
Check out my Seahawks vs. Cardinals same-game parlay predictions for Week 4 below, featuring Trey Benson and Jaxon Smith-Njigba.
Seahawks vs. Cardinals SGP predictions
SGP: Seahawks ML | Benson over 21.5 receiving yards | Smith-Njigba 70+ receiving yards (+390)
Seahawks ML (-115): I looked for every reason to back the home side in this divisional showdown and still came away thinking Seattle wins.
Both teams are 2-1, but the Cardinals have played some pretty bad opponents and don’t have the best underlying stats.
- Arizona has wins over the Carolina Panthers and New Orleans Saints, but recorded fewer total yards on offence in both games.
- The Cardinals then had the chance to beat the San Francisco 49ers without Brock Purdy and managed to score 15 points.
Seattle lost to the 49ers with Purdy and then scored 75 points combined over the next two weeks against the Pittsburgh Steelers and Saints.
For context, Arizona has scored 63 points in three games.
Both defences have been above average, but it’s the Seahawks’ offence that looks more reliable. Plus, they dominate this head-to-head matchup regardless of location.
Seattle has won seven straight games vs. Arizona, dating back to 2022.
Thursday Night Football SGP picks
Benson over 21.5 receiving yards (-112): With James Connor out, Benson should hold an immediate bell cow role in this offence.
He was splitting all the work with Connor before his Week 3 injury, with every carry but one going to the duo.
Emari Demercado will get run, no doubt, but Benson should be out there for 80% or more of the snaps.
He’s a strong pass catcher, generating eight catches on 11 targets through three weeks. So it only makes sense to target him as a receiver in this matchup.
- Seattle allows the most receiving yards per game to opposing running backs (78.0).
- That’s on the second-most receptions per game (7.3), so the flats are clearly being exposed.
Kyler Murray loves throwing short, and Benson is the clear No. 1 option in the backfield moving forward.
Murray has the fifth-lowest completed air yards per completion this season (2.7).
Smith-Njigba 70+ receiving yards (-190): A complete cleanout at the wide receiver position this offseason opened the door for Smith-Njigba to be a true WR1 in Seattle.
And he hasn’t disappointed. Take a look at his stats so far:
- 22 receptions (29 targets)
- 323 receiving yards (107.7/game)
- 3-0 against this wager
JSN ranks second in the league for receiving yards, and this is far from a tough matchup.
The Cardinals allow the most receptions (16.0) and sixth-most receiving yards per game (164.7) to wide receivers.
Only one other Seattle player has been targeted more than 10 times (Cooper Kupp, 15), so there’s a clear intention to target Smith-Njigba as much as possible.
Seahawks vs. Cardinals predictions made at 2:34 p.m. on 09/24/2025.
Spencer is a true sports junkie. A graduate of the Sports Journalism program at Centennial College, he first joined NorthStar Gaming as an intern in 2023. He is now a contributing writer. He loves finding the edge to bet on in all sports but has a deep passion for the NBA and UFC. Previous stops include Sportsnet.