Best MLB prop bets April 6: Take overs on Brent Rooker, Bryan Woo

MLB prop bets

On a Sunday filled with afternoon baseball, I’ve got a pair of MLB prop bets for two of the later games.

The pregame narrative: Bryan Woo isn’t known to have an elite strikeout arm, but I like the over on his Ks prop today (even with a lot of extra juice). Elsewhere, look for Brent Rooker to power up in an optimal hitting environment.

Check out the best MLB prop bets for April 6.

MLB prop bets

Best bet: Woo over 4.5 Ks (-150)

There’s a ton of juice on this prop, so I wouldn’t blame you for wanting to pair it with something to improve the price (pairing Woo over 4.5 Ks with under 9.5 total runs generates +104 odds, for example).

I do like this wager as is, though, given Woo’s track record against the San Francisco Giants and his overall numbers since last August.

Let’s start with his stats against the Giants. The interleague matchup yields a small sample, but it’s an encouraging one.

Against SF’s active roster, Woo has allowed four hits (.148 BA) while garnering eight strikeouts (28.6 K%). He faced the Giants once in 2023 and once in ’24, collecting seven Ks in both starts.

Though he’s not an eye-popping strikeout producer, Woo is conscientious about where he’s placing the ball. He led the majors with a 2.8% walk rate last season.

And from Aug. 1 through the start of the year, he’s cashed this bet in 10 of 12 starts — averaging 5.8 Ks per outing.

Key stat: The Giants have the sixth-highest K rate in the majors so far this year (26.0%0.

Best MLB picks

Rooker over 1.5 bases (+100): Rooker can hit the ball a mile, and he’s already shown that a handful of times in the early going this season.

The designated hitter has nine hits through nine games, and four of them left the yard. He also has an 89th-percentile xSLG (.630), per Baseball Savant, to go with an 87th-percentile barrel rate (18.5%).

Rooker is a free swinger, which is frustrating at times, but his low walk rate tells you he’s up there to hack. That’s a good thing for a bases prop.

Playing at elevation inside Coors Field, Rooker will be in baseball’s friendliest offensive environment on Sunday. Hopefully he sends something to the moon.

MLB prop picks made at 2:40 p.m. ET on 04/06/2025.

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Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.