Only the biggest names remain at the Final Four of the 2025 men’s NCAA tournament. It’s an almost unprecedented extent of heavyweight power.
The latest: All four No. 1 seeds are alive at the Final Four for just the second time in 45 years. The previous all-chalk iteration was 2008. Neither matchup is a pick’em, though, with the Duke Blue Devils and Florida Gators favoured to advance.
Check out the latest Final Four odds for the March Madness semifinal games on Saturday, April 5.
Final Four odds
Final Four odds as of 11:10 a.m. ET on 04/02/25.
Matchup: Florida Gators vs. Auburn Tigers
Date: Saturday, April 5: 6:09 p.m. ET
| Team | ML | Spread | Total |
| Florida | -163 | -2.5 (-112) | Over 159.5 (-110) |
| Auburn | +135 | +2.5 (-106) | Under 159.5 (-110) |
Matchup: Houston Cougars vs. Duke Blue Devils
Date: Saturday, April 5: 8:49 p.m. ET
| Team | ML | Spread | Total |
| Houston | +210 | +5 (-110) | Over 136 (-110) |
| Duke | -264 | -5 (-110) | Under 136 (-110) |
Final Four betting insights
- Florida was an underdog when it previously faced Auburn, and that turned into a 90-81 road win for the Gators. Five Florida players finished in double figures in that Feb. 8 matchup.
Florida is 7-3 ATS in March and has the best overall ATS record of the remaining teams (27-11).
- Auburn is 3-1 ATS during March Madness and has won three of its four games by 12+ points. The Tigers have already faced all three of their Final Four contemporaries: Florida (90-81 L), Duke (84-78 L), and Houston (74-69 W).
Also, unders are 5-1 in the Tigers’ past six games.
- Houston surely has vengeance on the mind after losing to Duke, 54-51, in last year’s Sweet 16. Aside from losing Jamal Shead to the NBA, this Cougars squad is largely the same as last year (eighth in minutes continuity, per KenPom.com).
Houston is on a 17-game win streak, and its opponent scored fewer than 70 points in 16 of those games.
- Duke has been dominant so far, as many expected. The Blue Devils have three wins of 20+ points, as well as a seven-point win over Arizona in which they never trailed after the first six minutes.
Cooper Flagg is doing his part, but he’s not alone. Kon Knueppel has back-to-back 20-point games, while Tyrese Proctor has scored at least 15 points in three of four matchups.
Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.