MLB is officially back, and with 28 teams in action on Thursday, the betting options are endless.
The latest: Jose Berrios gets the ball for the Toronto Blue Jays, who begin their season at home for the first time since 2019 and play the Baltimore Orioles. Later on, two Cy Young winners duel in Los Angeles when Blake Snell and the Los Angeles Dodgers host Tarik Skubal and the Detroit Tigers.
Check out the latest MLB Opening Day odds.
MLB Opening Day odds
MLB Opening Day Boost: Jays to win & Santander to homer. Bet now (+578)
Milwaukee Brewers vs. New York Yankees
Baltimore Orioles vs. Toronto Blue Jays
Philadelphia Phillies vs. Washington Nationals
Boston Red Sox vs. Texas Rangers
Pittsburgh Pirates vs. Miami Marlins
Atlanta Braves vs. San Diego Padres
Los Angeles Angels vs. Chicago White Sox
New York Mets vs. Houston Astros
San Francisco Giants vs. Cincinnati Reds
Cleveland Guardians vs. Kansas City Royals
Minnesota Twins vs. St. Louis Cardinals
Detroit Tigers vs. Los Angeles Dodgers
Chicago Cubs vs. Arizona Diamondbacks
Athletics vs. Seattle Mariners
Opening Day betting insights
- The Yankees have a Gerrit Cole-sized hole in their rotation and a Juan Soto-sized hole in their batting lineup. Still, New York is favoured on Opening Day with Carlos Rodon (3.96 ERA in 2024) starting against Milwaukee’s Freddy Peralta.
- Toronto’s future as a competitive ball club hangs in the balance this season, and starting hot at home will be crucial for success. Berrios has a 2.96 ERA against the Orioles since 2022 and logged two quality starts against them last year (both wins).
- Paul Skenes had a historic rookie season and starts his sophomore campaign against one of MLB’s weakest teams from 2024. Miami went 30-51 at home last season and counters with Sandy Alcantara, who is coming off his worst year as a starter (4.14 ERA, 113 ERA+).
- Detroit went 21-10 with Skubal on the mound last season but is an underdog on Thursday. That makes sense considering the Tigers will face the best offence in baseball on the road. Skubal likely won’t pitch deep into this game, and Los Angeles’ bullpen had the third-best ERA in 2024.
- One of the last games on Opening Day takes place in Seattle, where Logan Gilbert and the Mariners host the Athletics. Gilbert was picked by two of our staff writers to win the AL Cy Young and has held this A’s lineup to a .107 batting average in 97 plate appearances.
Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.