NFL Week 15 kicks off with a massive NFC West showdown on Thursday Night Football.
The pregame narrative: The San Francisco 49ers’ season is on its last legs, but they’re favoured at home against the Los Angeles Rams. I’m backing L.A. to cover an alt underdog spread in my +450 SGP, which also features prop bets on Puka Nacua and Isaac Guerendo.
Check out my Rams vs. 49ers same-game parlay predictions for Week 15 below.
Rams vs. 49ers same-game parlay predictions
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Parlay: Rams +3.5 + Nacua over 74.5 rec. yards + Guerendo anytime TD (+450)
Rams +3.5 (-137): I know Los Angeles is the road team on Thursday night, but I still don’t understand why it’s getting points against a suspect San Francisco squad.
The Rams beat the Niners, 27-24, back in September. More recently, the Rams are 5-2 straight up and against the spread since Week 7.
None of L.A.’s recent wins was bigger than its 44-42 defeat of the Buffalo Bills last Sunday. That same Buffalo team beat San Francisco, 35-10, the week before.
The 49ers are 2-5 ATS since Week 7. Unsurprisingly, not having Christian McCaffrey has been a problem. I expect them to either win close or not at all.
Other parlay picks
Nacua over 74.5 receiving yards (-205): The Rams sorely missed Nacua earlier this season, when he was sidelined with a knee injury.
What he’s accomplished in seven games since returning is exceptional:
- 10.1 targets/game
- 7.1 catches/game
- 96.1 yards/game
- 9+ targets and 75+ yards in 5/7 games
The Rams are at their best when they’re scheming to get the ball in Nacua’s hands. He had his best game of the season last week, which included 12 catches, 178 scrimmage yards and two touchdowns.
Nacua has cashed this prop in 10 of 15 games dating back to the 2023 season.
Guerendo anytime TD (-137): Guerendo is listed as questionable after battling a foot injury through the week, but ESPN’s Adam Schefter reported that he “plans to play” and said he “feels good.”
If he’s in there, I think Guerendo has a nice chance to score.
- Last week, in his first opportunity as a starter, Guerendo rushed 15 times for 78 yards and two TDs.
- Guerendo scored on both of his carries inside the five-yard line.
- The Rams’ defence is 24th in scoring and 28th in rushing yards allowed.
San Francisco’s running back room is exceptionally thin right now, but Guerendo is at least somewhat of a proven commodity. He should have some valuable opportunities as long as he’s on the field.
Picks made at 10:25 a.m. on 12/12/24.
Jordan enjoys writing data-driven game previews and analysis articles — especially for MLB markets or NFL/NBA props. And as a proud Ohio University grad, he’ll always have a soft spot for college sports (especially if the Bobcats are involved). Previous stops include mlb.com, Sportsnet and The Athletic.