The Buffalo Bills welcome the San Francisco 49ers to Orchard Park for Sunday Night Football.
The pregame narrative: Buffalo should maintain its perfect home record against an injured San Francisco squad. I’m backing Josh Allen to throw multiple touchdowns and also have prop bets on Christian McCaffrey and Jauan Jennings.
Check out my 49ers vs. Bills same-game parlay predictions for Week 13 below.
49ers vs. Bills same-game parlay predictions
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Parlay: Bills moneyline + Allen over 1.5 touchdown passes + McCaffrey over 49.5 rushing yards + Jennings over 34.5 receiving yards (+410)
Bills moneyline (-278): The Niners are banged up, missing superstars on both sides of the ball with Trent Williams and Nick Bosa out.
Brock Purdy is expected to play but he’s still battling a shoulder injury and that doesn’t bode well for San Fran’s sputtering offence, which is averaging just 19.6 points over its last five games.
Keeping up with the Bills at Highmark Stadium will be tough, as the squad owns a 5-0 record with a +15.8 average margin of victory there this season.
San Francisco’s season might be on the line but I expect Buffalo to keep things rolling under the bright lights.
Other parlay picks
Allen over 1.5 touchdown passes (+102): Entering play on Sunday, Allen was favoured to win the MVP.
A statement game tonight would go a long way in solidifying his case and I think he’s primed to dice up the Niners through the air.
Allen only has one TD pass in his last two games but recorded multiple in four straight before that.
He’s had at least 33 passing attempts in five consecutive games and should have more time to push the ball downfield with Bosa sidelined.
The Niners’ defence has been suspect this season and is missing a few big names in the secondary. All things considered, Allen is in a good spot to keep his 2.4 passing touchdowns per game pace at home.
McCaffrey over 49.5 rushing yards (-295): McCaffrey seems to have lost a step but I still like his chances of clearing this teased-down line.
The reigning offensive player of the year was held to just 31 yards on 11 carries last week but the game script didn’t work in his favour as the Purdy-less Niners were down huge to the Green Bay Packers early.
McCaffrey still logged an 82% snap count and should have a much bigger workload on SNF.
The Bills allow the fourth-most yards per rush (4.9) and five of the last six starting RBs to play them have cleared this total.
Jennings over 34.5 receiving yards (-345): Jennings has become San Fran’s WR1 with Brandon Aiyuk sidelined.
The fourth-year wideout leads the team in targets (65) and has a whopping 22 catches over his last three games. He went over this line in each of those contests while averaging 74.7 yards per game.
Jennings has cleared this mark in seven of nine on the season.
Picks made at 12:55 p.m. on 11/29/24.
Avery joined NorthStar Gaming as an intern in 2022 before stepping into a full-time role soon after. He loves betting on and analyzing golf — mainly because it’s easier than actually playing — but is a fan of all sports, from the NFL to the UFC.